Publications 1998


Department of Human Genetics


1998

Publicaties in ref. tijdschriften
Aalto-Setala K, Benlian P, Bowyer D, Hofker M, James RW, Poledne R, Steinmetz A. European Lipoprotein Club, report of the 20th annual conference. Atherosclerosis 137, 223-229, 1998.

Beverstock GC, Hansson K, Helderman-van den Enden ATJM, Bröcker-Vriends A, Klumper F, Bartelings M, Dobbe-van Meerendonk W, Roosmalen J van, Kolkman PH, Kanhai HH. A near false-negative finding of mosiac trisomy 21- a cautionary tale. Prenat Diagn 18, 742-746, 1998.

Boer M de, Bakker E, van Lierde S, Roos D. Somatic triple mosaicism in a carrier of X-linked chronic granulomatous disease. Blood 91, 252-257, 1998.

Boland CR, Thibodeau SN, Hamilton SR, Sidransky D, Eshleman JR, Burt RW, Meltzer SJ, Rodriguez-Bigas MA, Fodde R, Ranzani GN, Srivastava S. A national cancer workshop on microsatellite instability for cancer detection and familial predisposition, development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 58, 5248-5257, 1998.

Deutz-Terlouw PP, Losekoot M, Aalfs CM, Hennekam RCM. Asn540Thr substitution in the fibroblast growth factor receptor 3 tyrosine kinase domain causing hypochondroplasia. Hum Mutat 1, 62-65, 1998.

Dudok de Wit AC, Tibben A, Duivenvoorden HJ, Niermeijer MF, Passchier J, Trijsburg RW, Lindhout D, Meijers-Heijboer EJ, Frets PG, Lodder LN, Zoetewij MW, Klijn JGM, Brocker-Vriends A, van Haeringen A, Helderman ATJM, Hilhorst-Hofstee Y, Kant S, Maat-Kievit JA, Oosterwijk JC, van der Smagt JJ, Vegter-van der Vlis M, Vries-van der Weerd MACS, Zoeteweij MW, Bakker E, Devilee P, Losekoot M, Tops C, Cornelisse CJ, Vasen HFA. Distress in individuals facing predictive DNA testing for autosomal dominant late-onset disorders, Comparing questionnaire results with in-depth interviews. Am J Hum Genet 75, 62-74, 1998.

Ehnholm S, Willems van Dijk K, van ‘t Hof B, van der Zee A, Olkkonen VM, Jauhiainen M, Hofker M, Havekes L, Ehnholm C. Adenovirus mediated overexpression of human phospholipid transfer protein alters plasma HDL levels in mice. J Lipid Res 39, 1248-1253, 1998.

Ford D, Easton DF, Stratton M, Narod S, Goldgar D, Devilee P, Bishop DT, Weber B, Lenoir G, Chang-Claude J, Sobol H, Teare MD, Struewing J, Arason A, Scherneck S, Peto J, Rebbeck TR, Tonin P, Neuhausen S, Barkardottir R, Eyfjord J, Lynch H, Ponder BA, Gayther SA, Birch JM, Lindblom A, Stoppa-Lyonnet D, Bignon Y, Borg A, Hamann U, Haites N, Scott RJ, Maugard CM, Vasen H, Seitz S, Cannon-Albright LA, Schofield A, Zelada-Hedman M. Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. Am J Hum Genet 62, 676-689, 1998.

Forster EA, Jobling MA, Taylor PG, Donnelly P, Knijff P de, Mieremet R, Zerjal T, Tyler-Smith C. Jefferson father slave’s last child. Nature 396, 27-28, 1998.

Giles RH. Update-CBP/p300 transgenic mice. Trends Genet 14, 178-183, 1998.

Giles RH. Unshrouding the human genome. Mol Med Today 4, 238-239, 1998.

Giles RH, Dauwerse JG, van Ommen GJB, Breuning MH. Do human chromosomal bands 16p13 and 22q11-13 share ancestral origins? Am J Hum Genet 63, 1240-1242, 1998.

Giles RH, Peters DJM, Breuning MH. Conjunction dysfunction, CBP/p300 in human disease. Trends Genet 14, 178-183, 1998.

Giordano PC, Harteveld CL, Haak HL, Batelaan D, van Delft P, Plug RJ, Emonts M, Zanardini R, Bernini LF. A case of non- b-globin gene linked b- in a Dutch family with two additional a-gene defects, The common -a3.7 deletion and the rare IVS1-116(A®G) acceptor splice site mutation. Br J Haematol 103, 370-376, 1998.

Giordano PC, Harteveld CL, Michiels JJ, Terpstra W, Schelfhout LJDM, Appel IM, Batelaan D, van Delft P, Plug RJ, Bernini LF. Phenotype variability of the dominant b-thalassemia induced in four Dutch families by the rare cd 121 (G®T) mutation. Ann Hematol 77, 249-255, 1998.

Grewal PK, Todd LC, van der Maarel SM, Frants RR, Hewitt JE. FRG1, a gene in the FSH muscular dystrophy region on human chromosome 4q35, is highly conserved in vertebrates and invertebrates. Gene 216, 13-19, 1998.

Gruis NA, van der Velden PA, Bergman W, Frants RR. Genetics of familial atypical multiple mole-melanoma (FAMMM) syndrome in The Netherlands, how far have we come? Bull Cancer 85, 627-630, 1998.

Hoffer MJ, Sijbrands EJ, de Man FH, Havekes LM, Smelt AH, Frants RR. Increased risk for endogenous hypertriglyceridaemia is associated with an apolipoprotein C3 haplotype specified by the SstI polymorphism. Eur J Clin Invest 28, 807-812, 1998.

Hoffer MJV, Bredie SJH, Snieder H, Reymer PWA, Demacker PNM, Havekes LM, Boomsma DI, Stalenhoef AFM, Frants RR, Kastelein JJP. Gender-related association between – 93T ? G/D9N haplotype of the lipoprotein lipase gene and elevated lipid levels in familial combined hyperipidemia. Atherosclerosis 138, 91-99, 1998.

Hofker MH, Breuer M. Generation of transgenic mice. Meth Mol Biol 110, 63-78, 1998.

Hofker MH, van Vlijmen BJ, Havekes LM. Transgenic mouse models to study the role of APOE in hyperlipidemia and atherosclerosis. Atherosclerosis 137, 1-11, 1998.

Iacoviello L, Di Castelnuovo A, de Knijff P, D’Orazio A, Amore C, Arboretti R, Kluft C, Donati MB. Polymorphisms in the coagulation factor VII gene and the risk of myocardial infarction. N Engl J Med 338, 79-85, 1998.

Jong MC, Gijbels MJ, Dahlmans VE, van Gorp PJ, Koopman SJ, Ponec M, Hofker MH, Havekes LM. Hyperlipidemia and cutaneous abnormalities in transgenic mice overexpressing human apolipoprotein C1. J Clin Invest 101, 145-52, 1998.

Jong MC, Dahlmans VE, Princen HM, Hofker MH, Havekes LM. Effects of fenofibrate on hyperlipidemia and postprandial triglyceride metabolism in human apolipoprotein C1 transgenic mice. Atherosclerosis 141, S77-80, 1998.

Karafet T, de Knijff P, Wood E, Ragland J, Clark A, Hammer MF. Different patterns of variation at the X- and Y-linked microsatellite loci DXYS156X and DXYS156Y in human populations. Hum Biol 70, 979-992, 1998.

Kartheuser A, Walon C, West S, Breukel C, Detry R, Gribomont A-C, Hamzehloei T, Hoang P, Maiter D, Pringot J, Rahier J, Khan PM, Curtis A, Burn J, Fodde R, Verellen-Dumoulin C. Familial adenomatous polyposis associated with multiple adrenal adenomas in a patient with a rare 3' APC mutaiton. J Med Genet 36, 65-67, 1998.

Kooi AJ van der, Visser M de, van Meegen M, Ginjaar HB, van Essen AJ, Jennekens FGI, Jongen PJH, Leschot NJ, Bolhuis PA. A novel gamma-sarcoglycan mutation causing childhood onset, slowly progressive limb girdle muscular dystrophy. Neuromuscul Disord 8, 305- 308, 1998.

Kooi AJ van der, Ginjaar HB, Busch HG, Wokke JH, Barth PG, de Visser M. Limb girdle muscular dystrophy, a pathological and immunohistochemical reevaluation. Muscle Nerve 21, 584-90, 1998.

Kuivenhoven JA, Jukema JW, Zwinderman AH, de Knijff P, McPherson R, Bruschke AVG, Lie KI, Kastelein JJP, for the regression growth evaluation statin study group. N Engl J Med 338, 86-93, 1998.

Lakhani SR, Jacquemier J, Sloane JP, Gusterson BA, Anderson TJ, van de Vijver MJ, Farid LM, Venter D, Antoniou A, Storfer-Isser A, Smyth E, Steel CM, Haites N, Scott RJ, Goldgar D, Neuhausen S, Daly PA, Ormiston W, McManus R, Scherneck S, Ponder BAJ, Ford D, Peto J, Stoppa-Lyonnet D, Streuwing JP, Spurr NK, Bishop DT, Klijn JGM, Devilee P, Cornelisse CJ, Lasset C, Lenoir G, Barkardottir RB, Egilsson V, Hamann U, Chang-Claude J, Sobol H, Weber B, Stratton MR, Easton DF. Multifactorial analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutations. J Natl Cancer Inst 90, 1138-1145, 1998.

Lemmers RJLF, van der Maarel SM, van Deutekom JCT, van der Wielen MJR, Deidda G, Dauwerse HG, Hewitt J, Hofker M, Bakker E, Padberg GW, Frants RR. Inter- and intrachromosomal sub-telomeric rearrangements on 4q35, implications for facioscapulohumeral muscular dystrophy (FSHD) aetiology and diagnosis. Hum Mol Genet 7, 1207-1214, 1998.

Leppanen P, Luoma JS, Hofker MH, Havekes LM, Yla-Herttuala S. Characterization of atherosclerotic lesions in apo E3-leiden transgenic mice. Atherosclerosis 136, 147-152, 1998.

Maassen van den Brink A, Vergouwe MN, Ophoff RA, Saxena PR, Ferrari MD, Frants RR. 5-HTIB receptor polymorphism and clinical response to sumatripan. Headache 38, 288-291, 1998.

Maassen van den Brink A, Vergouwe MN, Ophoff RA, Naylor SL, Dauwerse HG, Saxena PR, Ferrari MD, Frants RR. Chromosomal localization of the 5-HT1F receptor gene, No evidence for involvement in response to sumatriptan in migraine patients. Am J Med Genet 77, 415-420, 1998.

Mesker WE, Ouwerkerk-van Velzen MCM, Oosterwijk JC, Bernini LF, Golbus MS, Kanhai HHH, van Ommen GJB, Tanke HJ. Two-colour immunocytochemical staining of gamma and epsilon type haemoglobin in fetal red cells. Prenat Diagn 18, 1131-1137, 1998.

Mitchison HM, Hofmann SL, Becerra CHR, Munroe PB, Lake BD, Crow YJ, Stephenson JBP, Williams RE, Hofman IL, Taschner PEM, Martin J-J, Phillippart M, Andermann E, Andermann F, Mole SE, Gardiner RM, O'Rawe AM. Mutations in the palmitoyl-protein thioesterase gene (PPT;CLN1) causing juvenile neuronal ceroid lipofuscinosis with granular osmiophilic deposits. Hum Mol Genet 7, 291-297, 1998.

Moghaddam PH, de Knijff P, Roep BO, Schipper RF, van der Auwera B, Naipal A, Gorus F, Schuit F, Giphart MJ and the Belgian Diabetes Registry. Genetic structure of IDDM1. Two seperate regions in the major histocompatibility complex contribute to susceptibility or protection. Diabetes 47, 263-269, 1998.

Moghaddam PH, de Knijff P, Schipper RF, Moghaddam PH, Kazemi M, Lambooij SLE, van der Meer R, Naipal A, Pesonen N, van der Slik A, Giphart MJ. Selective co-evolution of the D6STNFa microsatellite region with HLA class I and II loci. Tissue Antigens 52, 213-219, 1998.

Nagel HTC, Vandenbussche FPHA, Keirse MJNC, Oepkes D, Oosterwijk JC, Beverstock G, Kanhai HHH. Amniocentesis before 14 completed weeks as an alternative to transabdominal chorionic villus sampling, a controlled trial with infant follow-up. Prenat Diagn 18, 465-475, 1998.

Neuhausen SL, Godwin AK, Gershoni-Baruch R, Schubert E, Garber J, Stoppa-Lyonnet D, Olah E, Csokay B, Serova O, Lalloo F, Osorio A, Stratton M, Offit K, Boyd J, Caligo MA, Scott RJ, Schofield A, Teugels E, Schwab M, Cannon-Albright L, Bishop T, Easton D, Benitez J, King MC, Ponder BA, Weber B, Devilee P, Borg Å, Narod SA, Goldgar D. Haplotype and phenotype analysis of nine recurrent BRCA2 mutations in 111 families, results of an international study. Am J Hum Genet 62, 1381-1388, 1998.

Ommen GJB van, Knoppers BM, Cotton R. Strauss J, Povey S, Doggett N, Cavalli-Sforza L. HUGO’s midlife crisis, life begins at 40. Nature Genet 19, 113-114, 1998.

Ommen GJB van. The Human Genome Project and the role of genetics in health care. Clin Chem Lab Med 36, 515-517, 1998.

Oosterwijk JC, Mesker WE, Ouwerkerk-van Velzen MCM, Knepflé CFHM, Wiesmeijer KC, van den Burg MJM, Beverstock GC, Bernini LF, van Ommen GJB, Kanhai HHH, Tanke HJ. Development of a preparation and stained method for fetal erythroblasts in maternal blood, simultaneous immunocytochemical staining and FISH analysis. Cytometry 32, 170-177, 1998.

Oosterwijk JC, Mesker WE, Ouwerkerk-van Velzen MCM, Knepflé CFHM, Wiesmeijer KC, Beverstock GC, van Ommen GJB, Kanhai HHH, Tanke HJ. Fetal cell detection in maternal blood, a study in 236 samples using erythroblast morphology, DAB and HbF staining, and FISH analysis. Cytometry 32, 178-185, 1998.

Oosterwijk JC, Knepflé CFHM, Mesker WE, Vrolijk H, Sloos WCR, Pattenier H, Ravkin I, van Ommen GJB, Kanhai HHH, Tanke HJ Strategies for Rare-Event Detection , an approach for automated fetal cell detection in maternal blood. Am J Hum Genet 63, 1783-1792, 1998.

Oosterwijk JC, Mesker ME, Ouwerkerk-van Velzen MCM, Knepflé CFHM, Wiesmeijer KC, Beverstock GC, van Ommen GJB, Tanke HJ, Kanhai HHH. Prenat diagnosis of trisomy 13 on fetal cells obtained from maternal blood after minor enrichment. Prenat Diagn 18, 1082-1085, 1998.

Ophoff RA, Terwindt GM, Ferrari MD, Frants RR. Genetics and pathology of voltage-gated Ca2+ channels. Histol Histopathol 13, 827-836, 1998.

Ophoff RA, Terwindt GM, Frants RR, Ferrari MD. P/Q-type Ca2+ channel defects in migraine, ataxia and epilepsy. Trends Pharmacol Sci 19, 121-127, 1998.

Passos-Bueno MR, Richieri-Costa A, Sertie AL, Kneppers A. Presence of the Apert canonical S252W FGRFR2 mutation in a patient without severe syndactyly. J Med Genet 35, 677-679, 1998.

Phelan CM, Borg A, Cuny M, Crichton DN, Baldersson T, Andersen TI, Caligo MA, Lidereau R, Lindblom A, Seitz S, Kelsell D, Hamann K, Rio P, Thorlacius S, Papp J, Olah E, Ponder B, Bignon YJ, Scherneck S, Barkardottir R, Borresendale AL, Eyfjord J, Theillet C, Thompson AM, Devilee P, Larsson C. Consortium study on 1280 breast carcinomas, Allelic loss on chromosome 17 targets subregions associated with family history and clinical parameters. Cancer Res 58, 1004-1012, 1998.

Rolf B, Meyer E, Brinkmann B, de Knijff P. Polymorphism at the tetranucleotide repeat locus DYS389 in 10 populations reveals strong geographic clustering. Eur J Hum Genet 6, 583-588, 1998.

Rosenberg C, Navajas L, Vagenas DF, Bakker E, Vainzof M, Passos-Bueno MR, Takata RI, van Ommen GJB, Zatz M, den Dunnen JT. Clinical diagnosis of heterozygous dystrophin gene deletions by fluorescence in situ hybridization. Neuromuscul Disord 8, 447-452, 1998.

Schothorst EM van, Beekman M, Torremans P, Kuipers-Dijkshoorn NJ, Wessels HW, Bardoel AFJ, van der Mey AGL, van Ommen GJB, Devilee P, Cornelisse CJ. Paragangliomas of the head and neck region show complete loss of heterozygosity at 11q22-q23 in chief cells and the flow-sorted DNA aneuploid fractionA1. Hum Pathol 29, 1045-1049, 1998.

Schothorst EM van, Jansen JC, Grooter E, Prins DEM, Wiersinga JJ, van der Mey AGL, van Ommen GJB, Devilee P, Cornelisse CJ. Fouder effect at PGL1 in hereditary head and neck paraganglioma families from the Netherlands. Am J Hum Genet 63, 468-473, 1998.

Giles RH, Dauwerse HG, van Ommen GJB, Breuning MH. Do human chromosomal bands 16p13 and 22q11-13 share ancestral origins? Am J Hum Genet 63, 1240-1241, 1998.

Schothorst EM van, Jansen JC, Grooters E, Prins DEM, Wiersinga LJ, van der Mey AGL, van Ommen GJB, Devilee P, Cornelisse CJ. Founder effect at PGL1 in hereditary head and neck paraganglioma families from The Netherlands. Am J Hum Genet 63, 468-473, 1998.

Sijbrands EJG, Lombardi MP, Westendorp RGJ, Gevers Leuven JA, Meinders AE, van der Laarse A, Frants RR, Havekes LM, Smelt AHM. Similar response to simvastatin in patients heterozygous for familial hypercholesterolemia with mRNA negative and mRNA positive mutations. Atherosclerosis 136, 247-254, 1998.

Slooter AJC, van Duijn CM, Bots ML, Ott A, Breteler MMB, Voecht J de, Wehnert A, de Knijff P, Havekes LM, Grobbee DE, van Broeckhoven C, Hofman A. Apolipoprotein E genotype, atherosclerosis, and cognitive decline, the Rotterdam study. J Neurol Transm 53, 17-29, 1998.

Slooter AJC, de Knijff P, Hofman A, Cruts M, Breteler MMB, van Broeckhoven C, Havekes LM, van Duijn CM. Serum apolipoprotein E level is not increased in Alzheimer’s disease, the Rotterdam study. Neurosci Lett 248, 21-24, 1998.

Smits R, van der Houven van Oordt W, Luz A, Zurcher C, Jagmohan-Changur S, Breukel C, Khan PM, Fodde R. Apc1638N, a mouse model for familial adenomatous polyposis-associated desmoid tumors and cutaneous cysts. Gastroenterology 114, 275-283, 1998.

Stec I, Wright TJ, van Ommen GJB, de Boer PAJ, van Haeringen A, Moorman AFM, Altherr MR, den Dunnen JT. WHSC1, a 90 kb SET domain-containing gene, expressed in early development and homologous to a Drosophila dysmorphy gene maps in the Wolf-Hirschhorn syndrome critical region and is fused to IgH in t(4;14) multiple myeloma. Hum Mol Genet 7, 1071-1082, 1998.

Stevens M, van Duijn CM, Kamphorst W, de Knijff P, Heutink P, van Gool WA, Scheltens P, Ravid R, Oostra BA, Niermeijer MF, van Swieten JC. Familial aggregation in frontotemporal dementia. Neurology 50, 1541-1545, 1998.

Taine L, Goizet C, Wen ZQ, Petrij F, Breuning MH, Ayme S, Saura R, Arveiler B, Lacombe D. Submicroscopic deletion of chromosome 16p13.3 in patients with Rubinstein-Taybi syndrome. Am J Med Genet 78, 267-270, 1998.

Terwindt GM, Ophoff RA, Haan J, Vergouwe MN, van Eijk R, Frants RR, Ferrari MD. Variable clinical expression of mutations in the P/Q-type calcium channel gene in familial hemiplegic migraine. Dutch Migraine Genetics Research Group. Neurology 50, 1105-1110, 1998.

Terwindt GM, Haan J, Ophoff RA, Groenen SMA, Storimans CWJM, Lanser JBK, Roos RAC, Bleeker-Wagemakers EM, Frants RR, Ferrari MD. Clinical and genetic analysis of a large Dutch family with autosomal dominant vascular retinopathy, migraine and Raunaud’s phenomenon. Brain 121, 303-306, 1998.

Terwindt GM, Ophoff RA, Frants RR, Ferrari MD. Kanalopathieën, genetische verklaring voor migraine en andere paroxismale neurologische aandoeningen. Ned Tijdschr Geneeskd 142, 1015-1019, 1998.

Terwindt GM, Ophoff RA, Haan J, Sandkuijl LA, Frants RR, Ferrari MD. Migraine, ataxia and epilepsy, a challaging spectrum of genetically determined calcium channelopathies. Eur J Hum Genet 6, 297-307, 1998.

The Retinoschisis Consortium (including den Dunnen JT, Kraayenbrink T, Schooneveld M van, van de Vosse E, Jong PTVM de, ten Brink JB, Schuurman E, Tijmes N, van Ommen GJB, Bergen AAB.) Functional implications of the spectrum of mutations found in 234 cases with X-linked juvenile retinoschisis (XLRS). Hum Mol Genet 7, 1185-1192, 1998.

Tuerlings JHAM, de France HF, Hamers A, Hordijk R, Hemel JO van, Hansson K, Hoovers JMN, Madan K, Van der Blij-Philipsen M, Gerssen-Schoorl KBJ, Kremer JAM, Smeets DFCM. Chromosome studies in 1792 males prior to intra-cytoplasmic sperm injection, the Dutch experience. Eur J Hum Genet 6,194-200, 1998.

Verhoog LC, Brekelmans CTM, Seynaeve C, van den Bosch LMC, Dahmen G, van Geel AN, Tilanus-Linthorst MMA, Bartels CCM, Wagner A, van den Ouweland A, Devilee P, Meijers-Heijboer EJ, Klijn JGM. Survival and tumour characteristics of breast-cancer patients with germline mutations of BRCA1. Lancet 351, 316-321, 1998.

Vlijmen BJ van, Pearce NJ, Bergo M, Staels B, Yates JW, Gribble AD, Bond BC, Hofker MH, Havekes LM, Groot PH. Apolipoprotein E*3-Leiden transgenic mice as a test model for hypolipidaemic drugs. Arzneimittelforschung 48, 396-402, 1998.

Vlijmen BJ van, Mensink RP, van ‘t Hof HB, Offermans RF, Hofker MH, Havekes LM. Effects of dietary fish oil on serum lipids and VLDL kinetics in hyperlipidemic apolipoprotein E*3-Leiden transgenic mice. J Lipid Res 39, 1181-1188, 1998.

Vasen HF, van der Luijt R, Tops C, Slors JF. Molecular genetic tests in surgical management of familial adenomatous polyposis. Lancet 351, 1131-1132, 1998.

Vosse E van de, Walpole SM, Nicolau A, van der Bent P, Cahn A, Vaudin M, Ross MT, Durham J, Pavitt R, Wilkinson J, Grafham D, Bergen ABB, van Ommen GJB, Yates JRW, den Dunnen JT, Trump D. Characterization of SCML1, a new gene in Xp22, with homology tp developmental polycomb genes. Genomics 49, 96-102, 1998.

Wagner TM, Moslinger RA, Muhr D, Langbauer G, Hirtenlehner K, Concin H, Doeller W, Haid A, Lang AH, Mayer P, Ropp E, Kubista E, Amirimani B, Helbich T, Becherer A, Scheiner O, Breiteneder H, Borg A, Devilee P, Oefner P, Zielinski C. BRCA1-related breast cancer in Austrian breast and ovarian cancer families, specific BRCA1 mutations and pathological characteristics. Int J Cancer 77, 354-360, 1998.

Wajcman H, Kister J, Riou J, Galacteros, Girot R, Maier-Redelsperger M, Nayudu NVS, Giordano PC. A neutral aminoacid substitution in the a1b2 interface that modifies the electrophoretic mobility of hemoglobin. Hemoglobin 22, 11-22, 1998.

Willems van Dijk K, van Vlijmen BJ, van der Zee A, van ‘t Hof B, van der Boom H, Kobayashi K, Chan L, Havekes LM, Hofker MH. Reversal of hypercholesterolemia in apolipoprotein E2 and apolipoprotein E3-Leiden transgenic mice by adenovirus-mediated gene transfer of the VLDL receptor. Arterioscler Thromb Vasc Biol 18, 7-12, 1998.

Wijnen J, van der Klift H, Vasen H, Khan PM, Menko F, Tops C, Meijers-Heijboer H, Lindhout D, Moller P, Fodde R. MSH2 genomic deletions are a frequent cause of HNPCC. Nature 20, 326-328, 1998.

Wijnen JT, Vasen HF, Khan PM, Zwinderman AH, van der Klift H, Mulder A, Tops C, Moller P, Fodde R. Clinical findings with implications for genetic testing in families with clustering of colorectal cancer. N Engl J Med 339, 511-518, 1998.

Wuyts W, van Hul W, Boulle K de, Hendrickx J, Bakker E, Vanhoenacker F, Mollica F, L'decke HJ, Sitki Sayli B, Pazzaglia UE, Mortier G, Hamel B, Conrad EU, Matsushita M, Raskind WH, Willems PJ. Mutations in the EXT1 and EXT2 genes in hereditary multiple exostoses. Am J Hum Genet 62, 346-354, 1998.

Zelderen-Bhola SL van, Bovée JVMG, Wessels HW, Mollevanger P, Nijhuis JV, van Eendenburg JDH, Taminiau AHM, Hogendoorn PCW. Ring chromosome 4 as the sole cytogenetic anomaly in a chondroblastoma, A case report and review of the literature. Cancer Genet Cytogenet 105,109-112, 1998.

Publicaties in andere tijdschriften
Giordano PC, Harteveld CL. Hemoglobinopathieën in Nederland, de rol van de huisarts in dragerschapsdiagnostiek en preventie. Huisarts & Wetenschap 6, 290-295, 1998.

Harteveld CL.The molecular genetics of a-thalassemia, Structure and expression of the a-globin gene cluster. Tijdschr Kindergeneeskd 66, 136-137, 1998

Harteveld CL, Giordano PC. Systematische opsporing hemoglobinopathieën. Huisarts & Wetenschap 41, 585, 1998.

Andere academische publicaties
Bakker E, van Ommen GJB. Duchenne and Becker Muscular Dystrophy (DMD and BMD). In: Emery AEH (ed). Neuromuscular Disorders: Clinical and molecular genetics, pp. 59-78, 1998. ISBN 0-471-97817-5

Luijt RB van der, Fodde R. Denaturing gel gradient electrophoresis and its variant in mutation detection. In: Spurr NK, Young BD , Bryant SP (eds). ICRF handbook of genome analysis, pp. 495-510, 1998. ISBN0-632-03728-8

Ommen GJB van. Genoom en Geneeskunde. In: Galjaard H (ed). Genen in kaart. Mensen in of uit problemen, pp. 13-22, 1998. ISBN 90-6984-227-0

Ommen GJB van. Integration of gene and genome maps by multicolour-FISH and DNA-halohybridization. In: Hallen M (ed). Human Genome Analysis. pp. 365-374, 1998. ISBN 90-5199-409-5

Ommen GJB van , Bakker E. DNA-diagnostics: disclosing the human genome. In: Hennekam RCM (ed). Ballière's Clinical Paediatrics. Genetics for the clinician. pp. 179-195, 1998. ISBN 0-7020-2374-4

Proefschriften
Giles RH. Mutations of the CBP gene in human disease. Promotoren: GJB van Ommen, MH Breuning. 1998.

Giordano PC. Hemoglobinpathieën in Nederland. Diagnostiek, epidemiologie en preventie. Promotor: LF Bernini. 1998.

Harteveld CL. The molecular genetics of alpha-thalassemia. Structure and expression of the alpha-globin gene cluster. Promotor: LF Bernini. 1998.

Rooij KE de. Huntington’s disease; molecular genetics and biochemical studies. Promotor: GJB van Ommen. 1998.

Schothorst EM van. Genetics of hereditary head and neck paraganglioms (glomus tumours). Promotoren: GJB van Ommen, CJ Cornelisse. 1998.

Vosse E van de. Positional cloning in Xp22:towards the isolation of the gene involved in X-linked retinoschisis? Promotor: GJB van Ommen. 1998.

Patenten
Bakker E, Devilee P, Petrij-Bosch A, van Ommen GJ. A diagnostic kit for determining a predisposition for breast and ovarian cancer, materials and methods for such determination. European patent nr. 98928648.9